2nd Lord In 12th house
2)As 12th house is house of expenses and 2nd house is house of wealth so it general meaning is you expenses your wealth. But 2nd lord is placed 11th from own house which meaning is profit of wealth. So 2nd lord in 12th gives two ways results depending on its conditions.It is just common sense if you have no wealth how you expenses. So if 2nd lord is afflicted in 12th house it indicating you expenses more than yours earnings. If 2nd lord is well placed then you have deposit a lots o wealth. But expenses of your money is always with you because 2nd lord is placed in 12th house. It may also cause of luxurious life style because you are expenses his wealth on comfort and pleasure.
3) 2nd house belongs to bed pleasure so afflicted 2nd lord indicating you have expenses his wealth for getting or enjoying bed pleasure.For example some one expenses his wealth on immoral things such as on corrupt women or enjoying sexual pleasure.
4)12th house also belongs to spirituality or religious activities so 2nd lord in 12th house indicating native may expenses his wealth on spiritual matter or religious donation or religious tour or any religious activities. It may also cause for earning wealth through working for spirituality, religious placed or activity, religious or any spiritual trust. And 2nd house also belongs to speech so native may expenses his speech on religious work and earn through it.
5)12th house belongs to foreign matter and 2nd lord is placed in 12th house indicating native may earn through foreign sources. Native may go for foreign for earning or earn through any foreign things.
6)2nd lord in 12th may also cause for doing service for earning due to aspects on 6th house of service.
7)12th house also belongs to hospital so 2nd lord in 12th house also indicating native may expenses his wealth on hospitalization depending on any Marak affiliation. Other wise native may earn through hospital.
8)As 12th house also belongs to immoral activity or illegal activity so 2nd lord placed in 12th house indicating native may earn through illegal way. It may also cause for expenses his wealth on illegal activity or immoral things.
9)2nd lord in 12th house may cause for eye problem. 12th house belongs to sleeping and 2nd lord in 12th house indicating native may have any sleeping dieses.
10)2nd lord is 6th lord from 9th house and it is placed on 4th from 9th house so it may indicating native may not gets happiness from father.
11)When 2nd lord with 12th lord in 12th house it indicating native may be suffering regarding money matter because 2nd lord(lord of wealth) is afflicted by 12th lord(lord of expenses). Native may have huge expenses or loss due to this he may go to debits. It may also indicating 2nd lord is gaining Marak power so it may cause for death or loss of life. Family may be suffering from misfortune.
12)2nd lord is markesh and 12th lord is dussthan so if 2nd lord is afflicted in 12th house native may suffering from health problems or any life span trouble depending on horoscope.
13)2nd lord in 12th house may cause for name and fame of native depending on horoscope.
14)If you want to know effect of different planet in 12th house you may read Planet in 12th house.